"In my current position, I collaborate with our offices in the U.S., Canada, Scotland, and Finland. It was a struggle at first to always remember what day and time others were working in; however, I now have a great desktop application that tracks this for me so I have a quick reference to the information that I need."

"I do not have exposure to working around multiple time zones; however, this is something I could pick up on very quickly. With technology these days I am sure I could find some help with a handy phone or desktop application. Also, I am not opposed to working outside of business hours on the occasions where I would need to communicate with a client across the globe."

The interviewer wants to hear your honest answer to see if you have any familiarity with this situation. It can be a tricky thing to get used to and you may have to adjust your work hours to meet everyone's needs. Describe your willingness to be adaptable and make it work.