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Can you explain to me how radiation therapy kills cancer cells?

Answer examples and advice for how to answer this interview question for a Radiation Therapists interview

How to Answer

Demonstrate your knowledge by explaining how the medicines and machinery you are responsible for operating assist with the process of staving off cancer. Radiation equipment is specialized to target the cancerous cells while sparing the surrounding tissue. Talk about what is happening on a higher level, explaining the science behind it and how the treatment has proven to be effective.

Can you explain to me how radiation therapy kills cancer cells?

View user-submitted Answers

Can you explain to me how radiation therapy kills cancer cells?
1.
Radiation therapy uses high-energy radiation to kill cancer cells by damaging their DNA. It can either damage the DNA directly or create charged particles within the cells that will in turn damage the DNA. However, it is important that the radiation only be delivered to cancer cells because normal cells can be damaged too.
2.
Radiation kills cells that are damaged by cancer so that they cannot divide and spread keeping them localized.
3.
What radiation does is it targets the DNA of cells and induces damage that way and it works in two ways. It can damage the DNA to promote cell killing and it can damage the DNA to prevent stop DNA replication so that the cancer cells do not multiply.
4.
Radiation therapy targets dividing cells, majority of them in M phase and damages their DNA. When this has been damaged, cells are unable to divide and are killed.
5.
Radiotherapy works by damaging the DNA inside the tumor cells, destroying their ability to reproduce. It uses high-energy particles to destroy or damage cancer cells.
6.
High levels of radiation interact with the cancer cell DNA causing cellular death.
7.
Radiation therapy targets the tumor cells and destroys there ability to reproduce.
8.
Radiation therapy kills cancer cells by damaging their DNA (the molecules inside cells that carry genetic information and pass it from one generation to the next). Radiation therapy can either damage DNA directly or create charged particles (free radicals) within the cells that can in turn damage the DNA. Cancer cells whose DNA is damaged beyond repair stop dividing or die. When the damaged cells die, they are broken down and eliminated by the body’s natural processes.
9.
The ionising radiation kills cancer cells by destroying their DNA
10.
It destroys the DNA of the cancer cell therefor disabling its ability to reproduce.
11.
The radiation kills the cancer cells by damaging the dna of the cell and making it unreproducable.
12.
It can kill directly or indirectly. Directly by interacting with DNA of a cell and indirectly with interacting with H20 in the body.
13.
Radiation therapy alter the DNA of the cancer cells thus, preventing them from duplicating.
14.
Radiation targets and destroys the cancer cells by using a high energy beam.
15.
By indirect damsge to DNA caused by ionisation of water molecules within cells which leads to development of free radicals. It is these free radicals that cause splits in the DNA, leading to cell death.
16.
The radiation interacts with the cell cycle causing the cell to be unable to replicate and in turn dies. The cell begins to repair but before it can be completely repaired the radiation is then given again to completely break the cycle.
17.
It uses high energy X rays to interact with body tissue to produce ions which kill the tumor cell. Both electrons and photons can be used depending on the depth of the tumor.
18.
I t kills the cell in the cell cycle so it cannot divide and grow bigger.
19.
When we treat cancer cells with radiation, the intent on the radiation is to kill off the most "exterior" cancer cells that grow on the outside of the tumour, and as they die off, the intent is for the radiation to continue to kill each outside "layer" if you will of cancer cells to the point that it kills the entire tumour. Tumour cells are vascular by nature, so radiation aids with the killing of these cells, and the fractionation in which we treat patient is so the tumour cells do not have time to deoxygenate and regrow.
20.
The radiation interacts with the DNA chains of the cancerous cells. As they replicate rapidly and faster than healthy cells the radiaiton has a greater effect on them killing them/ stopping them from replicating.
21.
Radiation therapy kills cancer by treating the tumor bed which does not have any oxygen because treatment is fractioned, the healthy tissues can heal while the tumor bed slowly dies.
22.
Radiation targets the DNA of cells and affects their cells cycle. The cancer cells are unable to recover and repopulate between fractions whereas normal tissue cells are able to recover after a fraction.
23.
Radiation works by damaging the DNA within the cells. Once enough damage is done to the DNA through the accumulative effect of the radiation, the cell may not be able to function effectively through their cell cycle, which prevents cell division through mitosis.
24.
The photons or electrons that are produced break down the DNA of the cancer cell, which causes the cells death, it is therefore unable to replicate itself, more replication=more cancer.
25.
Radiation works by targeting and damaging cancer cells in small doses. Radiation is prescribed in such a way that each treatment is just enough to kill the cells over a period of time. This way, the outer most cells are sloughed away, the normal tissue has time to regenerate, and by the time the next dose of radiation is ready, the new outer cells are oxygenated and can be effectively damaged by the radiation.
26.
Kills the cancer cells at optimal dose amounts but in fractions. Gradually killing the unhealthy cells while the time interval allows healthy cells to maintain or heal.
27.
Radiation kills cells through 2 ways. The radiation can directly or indirectly kill cells through destroying DNA, forcing the cell to undergo apoptosis.
28.
High energy radiation is delivered by a linear accelerator, and is aimed at the tumor volume. When the ions clash with the tumor cells those cells are destroyed.
29.
Using special equipment, high doses of radiation is given to the cancer cells to get rid of them.
30.
Radiation therapy kills cancer cells as well as surrounding healthy cells. Radiotherapy kills cancer cells by destroying the cells DNA which means the cell cannot grow and divide.
31.
It does this by damaging the DNA found in those cells it can also create charged particles which damage the DNA.
32.
Radiation is disburse in the cancer field which will slowly break down the cancer skills during each treatment cycle. Because cancer cells can not repair.
33.
Radiation kills cancer cells which are in the process of dividing or preparing to divide, in the cell cycle, because this is the point at which they are most radiosensitive and the greatest damage can be done to the DNA. We want to take advantage of the 4Rs of radiobiology (repair, redistribution, reoxygenation, and repopulation), which is why we want to limit the time between treatments.
34.
Radiation therapy gives radiation to cancer cells. The radiation is energy that is carried by waves or streams of particles. The radiation damages the DNA that makes up the cancer cells and in turn kills it eliminating chance of reproduction.
35.
When a ppliying x-rays and inonising radiations we destroy the nucleus of the cancer cells stopping them from spreading and growing.
36.
Radiation therapy kills cancer cells by targeting them.
37.
Radiation therapy uses high level radiation to kill cancer cells with xrays, protons and electrons.
38.
Radiation damages the DNA directly and indirectly by creating particles that leads to damaging the DNA
39.
The carcinogenic cells have the reduced ability to repair the DNA single or double-strand breaks while healthy cells could repair at a faster rate. Hence, the fractionated delivery of radiation dose, ensures that the carcinogenic cells are eliminated while allowing enough time for healthy cells to recover between each treatment fraction.
40.
Radiation killls cancer cells by damaging the dna or by producing charged particles that in turn damages the cancer cells. Racia5ion can also damage the normal cell but normal cell are better at reparing themselves than cancer cells.
41.
Radiation damages the DNA within any cells it comes into contact with, the more radiation they recieve the higher damage they recieve which is why accuracy is so important. The radiotherapy is most effective in the mitosis stage of the cell cycle during the division of cells and least effective during the G0 resting stage.
42.
Radiation works to destroy the tumor cells. Radiation is either given as an external or internal treatment and targets the tumor cells while giving the surrounding healthy tissue a minimal dose.
43.
It damages the DNA in cells either indirectly with free radicals or directly with high linear energy transfer. Cancer cells have reduced capabilities to replace damaged DNA and so the cells die or pass on faulty DNA resulting in reduction of the tumor.
44.
By disrupting the DNA structure and prevengting growth in the cell cycle stage of division.
45.
It breaks the DNA of the cells and it prevents from infecting normal cells.
46.
By disrypiting the DNA structuyre of the cells and inhibits the abiklity of the cells to divide.
47.
Radiation therapy kills all cells, including cancer cells.
48.
Destroys the DNA of cells.
49.
It either directly or indirectly hits to target, which is the DNA. The direct hit goes straight to the DNA and the indirect hit goes to a water molecule that reproduces a free radical that then hits the DNA.
50.
Radiation kills cells through an indirect process called radiolysis which is the dissociation of water molecules forming extremely reactive -OH radicals which damage the cells enough to induce their apoptosis.

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