Would you be willing to work over 40 hours a week?

Before answering scheduling questions, it's important to be clear on expectations. If you haven't had a chance to clarify their scheduling needs, now would be the perfect time to ask!
It is a good idea to ask about the schedule expectations for this role. If they expect you to work 12 hour days, it would be important to know that before you immediately agree to anything. You want to be sure that you can meet their expectations.
If it turns out their schedule expectations won't work for you, think about what you can offer and see if you can meet in the middle. It's much better to discuss these things in an interview than to commit to a schedule that won't work for you.
Keep in mind that, in most states, an employer cannot demand that an employee work more than 44 hours per week.