"The most intriguing case I was exposed to during residency training was during my emergency medicine rotation. A young patient presented with lasting symptoms of insomnia and depression, and a family member brought them in. After many tests in the ER that evening, lab work was done up, and we were all left scratching our heads. Our attending recommended a neurologist get involved, and the patient was diagnosed with CJD the following week. I found this case interesting because a patient's symptoms can often lead you in many directions. Still, actual lab work, detective work, and teamwork ultimately lead to a correct diagnosis."