ViiV Healthcare Mock Interview
Practice 30 ViiV Healthcare interview questions covering HIV innovation, patient advocacy, and specialized pharmaceutical expertise.
Question 12 of 30
Are you familiar with the CCR5-32 mutation and its possible role in preventing or curing HIV?
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Rachelle Enns is an interview coach and job search expert. She works with candidates to perform their best in employment, medical, and post-secondary admission interviews.
CCR5-32 mutation is a rare genetic mutation that affects whether the receptor CCR5 is present in cells. CCR5 is the receptor used by HIV to gain entry into target cells. People who inherit the CCR5-32 mutation from one parent have reduced levels of the CCR5 receptor on their cells. People who inherit the CCR5?32 mutation from both parents completely lack the CCR5 receptor. In the case of Anthony Brown, also known as 'the Berlin patient,' Mr. Brown had life-threatening cancer and went through a very risk stem cell transplant procedure. The donor of the cells was known as a CCR5-32 homozygote (both of his parents lacked the CCR5 receptor). In Brown's case, his newly transplanted immune system lacks CCR5 receptors and is resistant to most strains of HIV. Knowledge of this receptor and the mutation has given HIV researchers increased hope of finding a way to cure HIV. Share any knowledge you have and don't forget, it's OK to ask questions.
Rachelle Enns is an interview coach and job search expert. She works with candidates to perform their best in employment, medical, and post-secondary admission interviews.
"I did a research paper on the Berlin patient and have tried to follow studies involving CCR5-32 mutation. I remember when HIV first became a big topic among healthcare professionals. In the beginning, we felt so discouraged, as if a cure was so far off. Although we still haven't found the cure, advances in medicine have brought us so much closer. I am waiting for the day that I will be able to witness patients who are cured completely."
Rachelle Enns is an interview coach and job search expert. She works with candidates to perform their best in employment, medical, and post-secondary admission interviews.
"I am very new to the field of HIV research, and have not yet learned about CCR5?32 mutation. Since the word mutation is used, I am curious to know if this is related to cell mutation that could get us a little closer to finding a cure?"
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Anonymous Answer
I am, and it is something I would be interested in either following or assisting with. It completely changed the approach and stigma of HIV/AIDS. Medicine has advanced greatly since HIV first became a big topic but each advancement has been in leaps and bounds, taking us closer to a cure.
Rachelle's Feedback
Fantastic start! Similar to the feedback in Q7, I recommend adding in more specifics of your understanding. This addition to your answer will further showcase your depth of knowledge.
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