Clinical Research Associate Mock Interview

Master 40 Clinical Research Associate interview questions covering GCP compliance, monitoring visits, and regulatory protocols.

Question 1 of 40

When making a 1L 1X PBS solution from the stock 10X concentration, how would you do it; which formula would you use?

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Krista Wenz

Krista Wenz has been on thousands of interview panels hiring EMS professionals and firefighters for public and private agencies.

Your interviewer will ask situation- and knowledge-based questions to understand how you outline your process and how well you can explain concepts to others. In this case, buffers and reagents come at concentrations that may or may not be suitable for direct use. This is a standard calculation used routinely as a Research Associate. Remember, you do not need to ask what PBS is as it's irrelevant to the result, and it's a common reagent in most laboratories.

Krista Wenz

Krista Wenz has been on thousands of interview panels hiring EMS professionals and firefighters for public and private agencies.

"100mL of 10X PBS and 900mL water is needed to make a 1X 1L solution. I would use the formula C1V1 C2V2 where C1 equals the initial concentration of the solution, V1 equals the initial volume of the solution, C2 represents the final concentration of the solution, and V2 is the final volume of the solution."

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40Clinical Research Associate Interview Questions & Answers

Role-Specific

1.When making a 1L 1X PBS solution from the stock 10X concentration, how would you do it; which formula would you use?

Competency

2.What is the purpose of a polymerase chain reaction (PCR)? Please provide an example of when you've run one in the past.

Competency

3.When receiving a new piece of equipment in the lab, give a brief explanation of what you would do to verify that the equipment works properly for its intended test.

Role-Specific

4.When your boss asks you to design an assay to detect a mutation using PCR, provide a list of 3 things you will do before testing and optimizing begin.

Communication

5.What is the difference between accuracy and precision?

Leadership

6.Give an example of a time you trained someone on a procedure. What went well and what did you learn from the experience?

Competency

7.In the scenario where your quality control fails, what troubleshooting steps would you take?

Competency

8.Give an example of the types of metadata and/or data analysis you are familiar with and have used in previous positions.

Critical Thinking

9.If you find yourself in a situation where your laboratory finds contamination, what troubleshooting steps would you take?

Capability

10.What is your experience with following procedure, preparing for, and being involved in a regulatory audit and/or inspections of any kind?

Critical Thinking

11.As a follow-up to the inspection question, what if you encounter a documentation error before the inspection? Is there a time when manipulating data is acceptable?

Role-Specific

12.If your laboratory needs a new piece of equipment, what steps would you take and what do you consider when bringing new equipment aboard?

Experience

13.What is your experience with cell culture and what types of cell culture-based assays have you performed?

Competency

14.When your boss asks you to get 5 aliquots each of 5 different samples to deliver to another department, what is being asked and how would you perform the task?

Role-Specific

15.A colleague asks you to ensure the glassware is sterilized for next week's experiments. What do you do?

Critical Thinking

16.Describe a time when you made a pipetting error and what you did to fix it.

Competency

17.How would you describe Good Laboratory Practices (GLP) to a new employee?

Experience

18.Describe your experience writing a standard operating procedure (SOP).

Leadership

19.How do you feel about supervising others and their work?

Ask The Interviewer

20.Do you have any questions for us?

Performance Based

21.Give me example of a large project or task you completed, the steps you took, and the overall outcome.

Problem Solving

22.How do you prioritize when you have multiple deadlines?

Discovery

23.What made you choose clinical research as a career path?

Career Goals

24.What have you done to further your professional development in the past 5 years?

Stress

25.How do you manage your time when under pressure?

Discovery

26.What is your greatest strength?

Tough

27.What is your greatest weakness? What are you doing to improve it?

Diligence

28.What do you know about our organization, and what makes you want to work with us?

Compatibility

29.Are you a detail-oriented person?

Tough

30.How would you handle an unethical request from a superior?

Communication

31.How do you describe your job to others who are unfamiliar with this line of work?

Discovery

32.What is your favorite stage of a clinical trial and why?

Compatibility

33.What part of your job is the most rewarding?

Discovery

34.What is your best piece of advice you would give to someone who is interested in pursuing a career as a Clinical Research Associate?

Conflict

35.Suppose you hear that a coworker is talking poorly about you behind your back. How would you respond?

Compatibility

36.Tell me about the data entry programs you are familiar with.

Direct

37.Why are you looking for a new job?

Communication

38.How would you respond if a trial participant asked you why they should participate in a clinical trial?

Role-Specific

39.This position requires traveling approximately 50% of the time, often on short notice. Will this be an issue for you?

Discovery

Clinical Research Associate Mock Interview

When making a 1L 1X PBS solution from the stock 10X concentration, how would you do it; which formula would you use?

40Clinical Research Associate Interview Questions & Answers

1.When making a 1L 1X PBS solution from the stock 10X concentration, how would you do it; which formula would you use?

2.What is the purpose of a polymerase chain reaction (PCR)? Please provide an example of when you've run one in the past.

3.When receiving a new piece of equipment in the lab, give a brief explanation of what you would do to verify that the equipment works properly for its intended test.

4.When your boss asks you to design an assay to detect a mutation using PCR, provide a list of 3 things you will do before testing and optimizing begin.

5.What is the difference between accuracy and precision?

6.Give an example of a time you trained someone on a procedure. What went well and what did you learn from the experience?

7.In the scenario where your quality control fails, what troubleshooting steps would you take?

8.Give an example of the types of metadata and/or data analysis you are familiar with and have used in previous positions.

9.If you find yourself in a situation where your laboratory finds contamination, what troubleshooting steps would you take?

10.What is your experience with following procedure, preparing for, and being involved in a regulatory audit and/or inspections of any kind?

11.As a follow-up to the inspection question, what if you encounter a documentation error before the inspection? Is there a time when manipulating data is acceptable?

12.If your laboratory needs a new piece of equipment, what steps would you take and what do you consider when bringing new equipment aboard?

13.What is your experience with cell culture and what types of cell culture-based assays have you performed?

14.When your boss asks you to get 5 aliquots each of 5 different samples to deliver to another department, what is being asked and how would you perform the task?

15.A colleague asks you to ensure the glassware is sterilized for next week's experiments. What do you do?

16.Describe a time when you made a pipetting error and what you did to fix it.

17.How would you describe Good Laboratory Practices (GLP) to a new employee?

18.Describe your experience writing a standard operating procedure (SOP).

19.How do you feel about supervising others and their work?

20.Do you have any questions for us?

21.Give me example of a large project or task you completed, the steps you took, and the overall outcome.

22.How do you prioritize when you have multiple deadlines?

23.What made you choose clinical research as a career path?

24.What have you done to further your professional development in the past 5 years?

25.How do you manage your time when under pressure?

26.What is your greatest strength?

27.What is your greatest weakness? What are you doing to improve it?

28.What do you know about our organization, and what makes you want to work with us?

29.Are you a detail-oriented person?

30.How would you handle an unethical request from a superior?

31.How do you describe your job to others who are unfamiliar with this line of work?

32.What is your favorite stage of a clinical trial and why?

33.What part of your job is the most rewarding?

34.What is your best piece of advice you would give to someone who is interested in pursuing a career as a Clinical Research Associate?

35.Suppose you hear that a coworker is talking poorly about you behind your back. How would you respond?

36.Tell me about the data entry programs you are familiar with.

37.Why are you looking for a new job?

38.How would you respond if a trial participant asked you why they should participate in a clinical trial?

39.This position requires traveling approximately 50% of the time, often on short notice. Will this be an issue for you?

40.How did you hear about this position?