You should briefly mention any systems you already have familiarity with. Then discuss how you would go about learning those you do not know. Perhaps you do best with independent learning and want to have some time to navigate through the system yourself or to watch online tutorials. If you do better learning from a live instructor, you might want to mention vendor training or spending time training with a coworker. Whatever your preferred approach, show the interviewer you are enthusiastic about jumping in and learning.

"As you already know from my resume, I have experience with Equifax and Lawson in my current job. Health E(fx) would be a new system to me though and I'm excited to have the chance to learn it. I would like to start off by reviewing any tutorials or training the vendor can provide and having a chance to look around the system myself. After that, I think I would get up to speed quickest by sitting with a team member and watching them use the system. It would give me the chance to see how the system works for the company's needs and to ask questions along the way."