The interviewer wants to know if there are any parts of this job that you are concerned about. Review the job posting in detail before the interview, and if there is anything that you are unsure of, this is the time to ask questions. If there is a travel requirement or a scheduling requirement that you are unable to fulfill, be honest about your concerns now rather than waiting until you are already working for the company. If there is a function of your position that you feel you may struggle with, ask for more information so that you can determine if this role is a good fit for you. If you feel that you can be successful in the role, reassure the interviewer of that at this time.