If you are interviewing with WME for representation as an actor: This question can be a tough one to answer at first, as it requires you to dig deep and honestly think about what you could be doing better, or where you could improve your situation as an actor. This query is similar to 'What are your weaknesses?'
We rarely want to focus on what we aren't doing well; however, the interviewer wants you to spotlight and discuss what you are doing to overcome an obstacle. Your response should focus on what you are doing to get past whatever is holding you back in your acting career.