If hired, are you available to work an occasional weekend?

The interviewer is looking to see your availability and flexibility with your schedule. If you answer that you are available to work weekends when needed, it shows that you are a team player and will be accommodating. If you cannot work weekends for some reason, explain why you would not be able to work occasional weekends. However, it might make you less likely to get hired if the interviewer needs an employee who can work weekends.