When answering this question, you want to come across as informed. There are many issues facing the medical industry. However, this question aims to reveal where your interests and motivators are and how informed and objective your opinions are. It also aims to reveal what interests you in your field.
Being an aspiring physician assistant means you need to take a keen interest in current events by closely following the challenges the medical industry faces. The interviewers want to see that you learn and keep up to date on what is developing and trending in your field. Discuss what you feel to be a primary concerning issue, and be sure to ask the interviewers for their opinions or what topics excite them. This is an opportunity to start a very insightful conversation.