At some point in any person's career, they have to work with a colleague or customer who is extremely difficult. Rather than looking to hear the fine details as to why this person was difficult, your interviewer will be looking to gain insight into how you personally handled the situation and others like it to ensure that a sound relationship was fostered even when you faced difficult circumstances. In your answer, some key things to focus on are your ability to be tolerant, understanding and a great communicator in these situations.