Do you have any limitations preventing you from flying, or doing this job safely?

What the interviewer is looking for is if you have any health issues or physical limitations that would prevent you from flying for long periods of time, or flying in general. These issues could include back or knee problems, vertigo, or even claustrophobia.

Depending on your region, it may be illegal for an interviewer to ask you about physical handicaps or disabilities. Keep this in mind when crafting your answer.