If hired, would you be available to work an occasional weekend, if needed?

The interviewer wants to see if you can fulfill the requirements of the job if hired. If there is a need for an occasional weekend, it most likely would have been posted in the job description. The interviewer wants to see if you have outside obligations that keep you from fulfilling their needs and if your schedule is flexible. To be an eligible candidate, it is recommended that you offer to work the occasional weekend if necessary.