The admissions interviewers have some tough decisions about who gets in and who doesn't. When choosing their students, they want to ensure that those they accept possess the necessary level of commitment to see their pursuits through. Therefore, they want to know that you've thought out a strategy in the event of not being accepted into Midwestern University this round or at all. Your answer to this question should exhibit an interest in this pursuit, which goes deeper than acceptance into this particular school this particular semester. Inform your interviewers that one rejection won't stop you. Talk about your plan to reapply if rejected, to get a head start on your studies, or to apply aggressively to other universities in other cities or even internationally. Whatever the path you choose, reveal your confidence and drive.