This position requires random drug testing twice a year. Do you have an issue with random drug testing?
The interviewer wants to hear that random drug testing will not be an issue for you if hired and that you are aware of this requirement. Some agencies require pre-employment and random drug testing for their employees, especially when working in law enforcement. If the agency has these requirements, they will typically put this in their job announcement, so it should not surprise you to hear this.
You want the interviewer to understand that you do not have an issue with this requirement because you have nothing to hide. Focus on letting the interviewer know you do not use illegal drugs or misuse prescription drugs.
If you have reason to believe you might fail a random drug test, you should avoid applying to this position until you address your drug problem. Most agencies have a zero-tolerance drug policy, so you should be clean before entering this line of work.
"No, I do not have an issue with random drug testing. I have never used drugs and do not take prescription medications, so my tests will always turn up negative."
"I saw that this is a requirement in your job announcement, and I do not have an issue with random drug testing. I do not use drugs and have nothing to hide."
