Be transparent about any questions you have regarding a work-from-home arrangement. If you are new to a work-from-home situation, it's completely okay to have reservations about certain aspects of this unique work arrangement. The interviewer wants you to reveal any hesitations, and they want to see that you are prepared for the realities that come with a home-based work situation.

Ask questions if you need to, but be sure also to present solutions. The overall vibe of your response should be positive. Your interviewer will not want to hear a laundry list of concerns. Choose one or two burning questions and stick with those. Show that you know your strengths and abilities rather than wait for the interviewer to fill in the blanks.