Ensure to review the job posting before the interview to see whether there are physical requirements. If there are physical requirements, the interviewer is assuming you reviewed the job posting before applying for the position and as such, there will not be any limitations.
If you answer no and physical requirements are clearly mentioned on the job posting, the interviewer may assume you are unprepared, i.e., you did not review the job posting and company before the interview, you applied for this position without reading the job posting because you want any job, and/or you are not serious about working for this particular company.