"If I don't match this year, I admit I'll be disappointed on Match Day, but I have other plans just in case. As we've discussed, I currently work at a local compounding pharmacy, and they've offered me a job as a pharmacist once I graduate. I've learned a lot there and know I could be happy working there after I graduate--at least for a while. If I don't match this year, I will apply again next year. I will work with my mentors to figure out some ways to continue learning and growing so that I can hopefully be a stronger applicant. I may volunteer in a hospital or shadow pharmacists and will definitely continue working on research with my professor. I think not matching this year would motivate me to push myself harder and help me reevaluate my goals and what I'm doing to get there."

Give a thoughtful response that shows you have a plan in the event you don't match. Discuss whether or not you'd apply again and what you'll do as an alternative. Ideally, you should assure your interviewers that not matching isn't a stopping point on your career path and that you'd continue to put your best foot forward.