You have a couple options with this question. You can think of some weaknesses or skills you need to brush up on. You could also think about some skills you would like to acquire in this new role. Maybe learning how to handle the administrative side will help you learn a new software. If you decide to talk about one of your weaknesses, be sure to focus on how you are taking action to improve it. If you are a people-pleaser, explain how you are learning to say "maybe" before committing to doing something.