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Glenmark Pharmaceuticals Interview
Questions

30 Questions and Answers by Darby Faubion
Darby Faubion has been a Nurse and Allied Health Educator for over twenty years. She has clinical experience in several specialty areas including pediatrics, medical-surgical, critical care, and hospice.

Question 1 of 30

What are some examples of solvents?

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Glenmark Pharmaceuticals Interview Questions

    1.

  1. What are some examples of solvents?
    • A solvent is a substance that can dissolve a solute resulting in a solution. A solvent is usually a liquid but it can also be solid or a gas. Share your knowledge of solvents and how they are used with the interviewer.

      Darby's Answer #1

      "Solvents are used to help create a solution. The most often used solvent is water, which can be used to improve solubility and stability."

      Darby's Answer #2

      "Solvents can be in solid or gas form. They are used to create a solution. Some solvents are non-aqueous like glycerol and ethanol; they are generally used for a lipophilic drug."

    2.

  1. Can you explain a possible problem that may arise with processing tablets?
    • While there are any number of issues that may arise when processing medications, there are a few that are more common when processing tablets. Those include: capping, lamination, and moddling. Explain what happens during one of this issues.

      Darby's Answer #1

      "One of the problems I can think of that may arise when processing tablets is lamination. Lamination is the term used to describe the separation of tablets into two or more layers."

      Darby's Answer #2

      "There are a few complications that come to mind when I think about tablet processing. Capping is either a partial or complete separation of a tablet top or bottom crown. Another possible problem I can thing of is mottling, which is unequal colour distribution of a tablet."

    3.

  1. Do you know what a viscosity imparting agent is?
    • Viscosity imparting agents are used when it is necessary or desirable to increase or decrease the viscosity of a liquid either to make it more palatable or to improve pour ability.

      Darby's Answer #1

      "Viscosity imparting agents are also called thickening agents. One type of viscosity imparting agents is a viscosity enhancer. Enhancers increase increase the thickness to help improve the taste and make it easier to pour."

      Darby's Answer #2

      "Viscosity imparting agents help to make a liquid easier to pour and improve the taste. Viscosity enhancers make liquids thicker and viscosity modifiers make them thinner."

    4.

  1. Glenmark Pharmaceuticals values its employees and strives to create a team atmosphere. Do you consider yourself a "team player"?
    • Almost everyone says yes to this question. But it is not just a yes/no question. You need to provide behavioral examples to back up your answer.

      Darby's Answer #1

      "Yes, I do consider myself a team player. I believe when we all work together we can accomplish so much more than if we try to do things by ourselves without insight from others."

      Darby's Answer #2

      "I am glad to know that Glenmark Pharmaceuticals Ltd. values the efforts of teamwork. I have always made an effort to work well with others and to contribute my strengths to the group in an effort to accomplish a goal together."

    5.

  1. At Glenmark Pharmaceuticals we like to encourage employees to have a healthy balance between work and their personal lives. What are some things you like to do to help you unwind and create balance in your life?
    • No matter what profession a person chooses, everyone needs some time to unwind and relax. Psychologists today say that a healthy balance in life allows a person to recharge and refocus which can result in better productivity at work. The interviewer simply wants to know what you do for you. Maybe you have a favorite pass-time or hobby. This is yet another way for the interviewer to get to know you as a person.

      Darby's Answer #1

      "One of my favorite pass-times is writing. After a busy day at work, I like to journal or write articles for a blog that I author. Both of these forms of writing allow me to release any feelings of frustration I may experience, especially after a stressful day or a difficult situation at work. The writings in my journal are private and my way of 'letting it all out.' The blog articles, on the other hand, are my way of using creative writing to share stories with my followers."

      Darby's Answer #2

      "I really enjoy working out at the gym and, I also take a kickboxing class twice weekly. After a good workout or class, I always feel like I can rest better and wake up energized and ready for the next day."

    6.

  1. What is the difference in a syrup and a suspension?
    • There is a slight difference in syrup and suspension products that can cause ineffective use in clinical effects. Understanding the difference between the two is especially important when educating patients on proper use. Show your understanding of the differences.

      Darby's Answer #1

      "In syrups, drug particles are distributed evenly throughout the solution. In suspensions, the drug particles do not completely dissolve in the solution which means they are not evenly distributed. It is important to educate patients who are using a suspension to shake the bottle well before dispensing the prescribed amount."

      Darby's Answer #2

      "Syrups are often viscous due to a high concentration of sugar which makes them more palatable, especially for younger children. Because drug particles in a suspension do not completely dissolve in the solution, they often settle at the bottom of the bottle making the suspension have two layers. Properly shaking a suspension before administration is helpful in combining the particles in the poured solution."

    7.

  1. What type of pharmaceutical excipient is carboxymethyl cellulose?
    • Carboxymethyl cellulose is an example of a disintegrant. Disintegrants are added to drug formulations, which assist to breakup tablets and contents of capsules into smaller particles for quick dissolution when it comes in contact with water in the GI tract.

      Darby's Answer #1

      "Carboxymethyl cellulose is a disintegrant excipient. It helps to break down medications in the gastrointestinal tract."

      Darby's Answer #2

      "It is classified as a disintegrant. Disintegrants, ideally, exhibit poor solubility and poor gel formation capacity. They are useful in the digestive tract where they mix with water and hellp to break the contents of capsules or tablets into pieces that are smaller are more easily absorbed."

    8.

  1. What can you tell me about buffering agents?
    • Buffering agents dissolve within a solvent and are used to help enable a solution to resist any change in pH should an acid or an alkali be added. Understanding different agents that may be used in a drug is important for those developing them. Share your knowledge with the interviewer.

      Darby's Answer #1

      "A buffering agent is used to help balance the pH in a solution. Examples include citrates or phospates."

      Darby's Answer #2

      "The choice of a buffer depends on the pH of a solution and the buffering capacity needed. They should have a low toxicity and be non-irritant A few examples include carbonate, gluconates, and lactates."

    9.

  1. What makes you think you will be successful at Glenmark Pharmaceuticals?
    • Rather than just sharing how you have gone above and beyond expectations in the past, focus on how your qualities will help you to meet and exceed expectations with Glenmark Pharmaceuticals Ltd.. Discuss the reasons why will you be great at this job. Talk about your qualifications and skills that will help you to do this job well. If you can, match your strengths to the requirements outlined in the job description.

      Darby's Answer #1

      "I know I will be successful in this role because I have been working in this industry for five years with great training and mentorship. I have a solid understanding of X, Y, and Z (skills listed in the job description). Also, I have all of my updated certifications as outlined in your job description. I am well-prepared for this next step in my career."

      Darby's Answer #2

      "I believe my success with Glenmark Pharmaceuticals Ltd. will come from having all of the hard skills that you are looking for, whether learned in school or gained through work experience. I know all the key players in this region and stay informed of best practices."

    10.

  1. What is a humectant, and can you provide an example?
    • A humectant attracts and retains the moisture in the nearby air via absorption, drawing the water vapor into and/or beneath the organism's surface. Humectants absorb water vapors from the atmosphere until a certain degree of dilution is attained. Aqueous solutions of humectants can reduce the rate of loss of moisture. Share your knowledge with the interviewer.

      Darby's Answer #1

      "Humectants attract moisture to help an organism achieve a desired level of dilution. Two types of humectants are inorganic humectants and organic humectants. Inorganic humectants Because of compatibility problems and their corrosive nature, inorganic humectants are not frequently used in cosmetics. Calcium chloride is an example. Organic humectants are widely used in cosmetics. The most commonly used organic humectants are glycerol, ethylene glycol, polyethylene glycol (PEG), diethylene glycol, tri ethylene glycol, propylene glycol, dipropylene glycol, glycerin, sorbitol, mannitol, glucose."

      Darby's Answer #2

      "Humectants are used to dilute a substance by attracting and retaining moisture. One type of humectant is metal organic humectants. These are limited used in cosmetics because of compatibility problems, corrosive nature and pronounced taste. One example of this class of humectants is sodium lactate."

    11.

  1. What are some key factors to consider in a manufacturing facility's design?
    • Facility design is very important in ensuring the flow of production is done effectively and runs smoothly. Understanding some of the key design essentials is important. Share any knowledge you may have regarding design importance.

      Darby's Answer #1

      " In the critical areas, the flow of air should be in one direction with enough velocity to prevent the particles from closing the area. Also, temperature, as well as humidity, should be regulated."

      Darby's Answer #2

      "If any contaminants are being generated in an area, there should be an efficiently working HVAC system to remove and prevent the contaminants from spreading to other areas. Ventilation dampers and other services should be positioned for maintenance purpose in a place away from the production area for easy access."

    12.

  1. Can you explain what an excipient is and one of its possible uses?
    • An excipient is a pharmacologically inactive substance formulated alongside the active pharmaceutical ingredient of a medication. Excipients have various uses. Share your knowledge with the interviewer.

      Darby's Answer #1

      "An excipient is a substance that has no active value that is used with the active ingredient of a pharmaceutical medication. One use of excipients is as a binder. Binders hold the ingredients in a tablet together."

      Darby's Answer #2

      "Excipients are used in the production of a medication for multiple reasons. They have no value as far as an active ingredient, but are used along with the active ingredient. They are often used as fillers. Fillers typically also fill out the size of a tablet or capsule, making it practical to produce and convenient for the consumer to use."

    13.

  1. What is a parenteral medication?
    • Parenteral medications are sterile dosage forms administered by injections thorough one more layers of the skin. Give the interviewer an example of a parenteral medication or route of administration.

      Darby's Answer #1

      "Parenteral medications are medications that are given through layers of the skin, such as IV therapy or an injection. If the medication is administered correctly, it will be sterile."

      Darby's Answer #2

      "Parenterals are any medication that are given through the skin. A Rocephin injection is one example. Also, intravenous medications are considered parenterals."

    14.

  1. Why did you choose a career in pharmaceutical manufacturing?
    • There are many career opportunities within the pharmaceutical industry. Questions like this give the interviewer an opportunity to know you. Share your thoughts about your career choice.

      Darby's Answer #1

      "I always wanted a career in the healthcare industry, but I wasn't sure if a hospital setting was for me. I did some research into different health-related career opportunities and really felt like working with pharmaceutical manufacturing would be an opportunity for me to provide a way to help people."

      Darby's Answer #2

      "I have always been fascinated with chemistry. I also wanted to do something to provide care for others. I felt like manufacturing pharmaceuticals would allow me to do both. I have never considered any other career."

    15.

  1. What are some types of additives, and can you provide an example?
    • Additives are used to increase the stability of a solution. Types of additives include: preservatives, anti-oxidants, and synergists. Explain what one of these types of additives does and give an example for the interviewer.

      Darby's Answer #1

      "One example of an additive is an anti-oxidant. It is used to prevent the auto oxidation of a drug in the formulation. An anti-oxidant may be ascorbic acid. Synergists are another additive that is used to enhance the activity of anti-oxidants. An example of a synergist is
      tartaric acid."

      Darby's Answer #2

      "Preservatives are a type of additive that are used to prevent microbial growth in the drug formulation. Phenyl mercuric acetate is an example of a preservative, as well as benzalkonium chloride."

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